- Scottie Thompson (2 movies)
- Scotty Leavenworth (1 movie)
- Scroobius Pip (1 movie)
- Seamus Moroney (1 movie)
- Seamus O'Hara (1 movie)
- Sean A. Rosales (1 movie)
- Sean Anthony Moran (1 movie)
- Sean Astin (6 movies)
- Sean Avery (2 movies)
- Sean Baker (1 movie)
- Sean Barrett (1 movie)
- Sean Bean (10 movies)
- Sean Biggerstaff (2 movies)
- Sean Blakemore (1 movie)
- Sean Bott (1 movie)
- Sean Boyd (3 movies)
- Sean Bridgers (2 movies)
- Sean Buckley (1 movie)
- Sean Buxton (1 movie)
- Sean Cameron Michael (2 movies)
- Sean Carrigan (1 movie)
- Sean Carvajal (1 movie)
- Sean Close (1 movie)
- Sean Coleman (1 movie)
- Sean Connery (3 movies)
- Sean Cronin (2 movies)
- Sean Cullen (1 movie)
- Sean Delaney (1 movie)
- Sean Devine (1 movie)
- Sean Duggan (1 movie)
- Sean Edward Frazer (1 movie)
- Sean Francis George (1 movie)
- Sean Gerace (1 movie)
- Sean Giambrone (1 movie)
- Sean Gildea (2 movies)
- Sean Gormley (1 movie)
- Sean Grennan (1 movie)
- Sean Gunn (4 movies)
- Sean Guse (1 movie)
- Sean Hannity (1 movie)
- Sean Harris (3 movies)
- Sean Hayes (1 movie)
- Sean Hennigan (1 movie)
- Sean Hoy (1 movie)
- Sean Huze (1 movie)
- Sean J. Dillingham (1 movie)
- Sean Kleier (1 movie)
- Sean Lawlor (2 movies)
- Sean Liang (1 movie)
- Sean Lynch (1 movie)