- Sam Robards (2 movies)
- Sam Spruell (2 movies)
- Sam Worthington (2 movies)
- Samantha Marsden (2 movies)
- Samantha Russell (2 movies)
- Sampda Sharma (2 movies)
- Samuel Le (2 movies)
- Samuel Witwer (2 movies)
- Sandra Bernhard (2 movies)
- Sandra Macat (2 movies)
- Sandy Fox (2 movies)
- Sanjeev Bhaskar (2 movies)
- Santos Morales (2 movies)
- Sara Sohn (2 movies)
- Sarah Danielle Madison (2 movies)
- Sarah Douglas (2 movies)
- Sarah Flind (2 movies)
- Sarah Jessica Parker (2 movies)
- Sarah McLeod (2 movies)
- Sarah Minnich (2 movies)
- Sarah Paulson (2 movies)
- Sarah Peirse (2 movies)
- Sarita Choudhury (2 movies)
- Sasha Alexander (2 movies)
- Sasha Spielberg (2 movies)
- Saul Rubinek (2 movies)
- Saverio Guerra (2 movies)
- Scott Adsit (2 movies)
- Scott Alan Smith (2 movies)
- Scott Capurro (2 movies)
- Scott Eastwood (2 movies)
- Scott G. Anderson (2 movies)
- Scott Grimes (2 movies)
- Scott Heindl (2 movies)
- Scott Hunter (2 movies)
- Scott Lawrence (2 movies)
- Scott Michael Morgan (2 movies)
- Scott Perry (2 movies)
- Scott Shepherd (2 movies)
- Scott Spiegel (2 movies)
- Scottie Thompson (2 movies)
- Sean Avery (2 movies)
- Sean Biggerstaff (2 movies)
- Sean Bridgers (2 movies)
- Sean Cameron Michael (2 movies)
- Sean Cronin (2 movies)
- Sean Gildea (2 movies)
- Sean Lawlor (2 movies)
- Sean Meehan (2 movies)
- Sean Whalen (2 movies)