- Omar Orozco (1 movie)
- Omar Patin (1 movie)
- Omar Sy (5 movies)
- Omari Bernard (1 movie)
- Omari Hardwick (2 movies)
- Omer Barnea (1 movie)
- Omid Abtahi (1 movie)
- Omid Djalili (3 movies)
- Omri Rose (1 movie)
- Ona Harris (1 movie)
- Onalee Ames (1 movie)
- Ondřej Vetchý (1 movie)
- Onira Tares (1 movie)
- Onix Serrano (1 movie)
- Onofrio Mancuso (1 movie)
- Onyemachi Ejimofor (1 movie)
- Oona Laurence (2 movies)
- Ooooota Adepo (1 movie)
- Ophelia Lovibond (4 movies)
- Ophélie Jonard (1 movie)
- Oprah Winfrey (2 movies)
- Oraldo Austin (1 movie)
- Orbert Rogers (1 movie)
- Orestes Matacena (2 movies)
- Oriana Lacono (1 movie)
- Orion Lee (1 movie)
- Orion McCabe (1 movie)
- Orla Johannes (1 movie)
- Orlando Bloom (11 movies)
- Orlando Gonzalez (1 movie)
- Orlando James (1 movie)
- Orlando Jones (2 movies)
- Orlando Lucas (1 movie)
- Orlando Thor Newman (1 movie)
- Orli Gottesman (1 movie)
- Orly Schuchmacher (1 movie)
- Orrin Hatch (1 movie)
- Orso Maria Guerrini (1 movie)
- Orson Bean (2 movies)
- Orto Ignatiussen (1 movie)
- Orwin C. Harvey (1 movie)
- Os Leanse (1 movie)
- Osamu Shigematu (1 movie)
- Oscar Avila (1 movie)
- Oscar Balderrama (1 movie)
- Oscar Beregi Jr. (1 movie)
- Oscar Fabila (1 movie)
- Oscar Gale (1 movie)
- Oscar Isaac (6 movies)
- Óscar Jaenada (4 movies)