Unlucky assassin Ladybug is determined to do his job peacefully after one too many gigs gone off the rails. Fate, however, may have other plans, as Ladybug’s latest mission puts him on a collision course with lethal adversaries from around the globe—all with connected, yet conflicting, objectives—on the world’s fastest train.
Reuben Feffer (Ben Stiller) is a guy who’s spent his entire life playing it safe. Polly Prince (Jennifer Aniston) is irresistible as a free-spirit who lives for the thrill of the moment. When these two comically mismatched souls collide, Reuben’s world is turned upside down, as he makes an uproarious attempt to change his life from middle-of-the-road to totally-out-there!